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Scientific reference list

  • Kwon, J., Kim, Y., Lanuza, A. et al. Formation of matter-wave polaritons in an optical lattice. Nat. Phys. (2022).
  • T.Kubasova, M.Horvath, K. Kocsis and M.Fenyö: Effect of visible light on some cellular and immune parameters. Immunology and Cell Biology, 1995, 73; 239-244. M.Fenyö, J.Mandl and A.Falus: Opposite effect of linearly polarized light on biosynthesis of interleukin-6 in a human B lymphoid cell line and peripheral human monocytes. Cell Biology International, 2002, 26(3); 265-269.
  • T.Kubasova, M.Fenyö, Z.Somosy, L.Gazso and I.Kertesz: Investigations on biological effect of polarized light. Photochemistry and Photobiology, 1988, 48; 505-509.
  • P.Bolton, M.Dyson and S.Young: The effect of polarized light on the release of growth factors from the U-937 macrophage-like cell line. Laser Therapy, 1992, 2(3); 33-37.
  • I.Kertesz, M.Fenyö, E.Mester and G.Bathory: Hypothetical physical model for laser dissimulation. Optics and Laser Technology, 1982, 16; 31-32.
  • K.A.Samoilova, K.D.Obolenskaya, A.V.Vologdina, S.A.Snopov and E.V.Shevchenko: Single skin exposure to visible light induces rapid modification of entire circulation blood - 1. Improvement of rheologic and immune parameters. Progress in Biomedical Optics/Proceedings of Low-Power Light on Biological Systems, 1998, IV; 90-103.
  • J.E.Roberts: Visible light induces changes in the immune response through an eye-brain mechanism (photoneuroimmunology), Journal of Photochemistry and Photobiology, B: Biology, 1995, 29(1); 3-15.

Wound

  • Al-Kader, Ahmed Mamdouh Mohamed Abd; Hassan, Maha A; Elsayed Hisham, Galal Mahran; Mowafy Zakaria Mowafy Emam.JMSCR Volume 03 Issue 05 May 2015
  • El-Deen, Heba Bahey; Fahmy, Seham; Ali, SA; El-Sayed, W.M. Polarized light versus light-emitting diode on healing of chronic diabetic foot ulcer . ROMANIAN J. BIOPHYS., Vol. 24, No. 2, P. 000–000, BUCHAREST, 2014
  • L.Medenica and M.Lens: The use of polarised polychromatic non-coherent light alone as a therapy for venous leg ulceration. Journal of Wound Care, 2003, 12(1); 37-40.
  • S.Monstrey, H.Hoeksema, H.Saelens, K.Depuydt, M.Hamdi, K.Van Landuyt and P.Blondeel: A conservative approach for deep dermal burn wounds using polarised-light therapy. British Journal of Plastic Surgery, 2002, 55; 420-426.
  • P.Iordanou, G.Baltopoulos, M.Giannakopoulou, P.Bellou and E.Ktenas: Effect of polarized light in the healing process of pressure ulcers. International Journal of Nursing Practice, 2002, 8(1); 49-55.
  • S.Monstrey, H.Hoeksema, K.Depuydt, G.Van Maele, K.Van Landuyt and P.Blondeel: The effect of polarized light on wound healing. European Journal of Plastic Surgery, 2002, 24(8); 377-382.
  • Invited commentary: W.Vanscheidt, The effect of polarized light on wound healing. European Journal of Plastic Surgery, 2002, 24(8); 383.
  • Colic MM, Vidojkovic N, Jovanovic M, Lazovic G. The use of polarized light in aesthetic surgery. Aesthetic Plast.Surg. 2004;28(5):324-7.
  • Tomashuk IP, Tomashuk II. [Clinical efficacy of alprostan in combination with "Bioptron-II" rays and iruxol-miramistin in the treatment of the diabetic foot complicated by atherosclerosis]. Klin.Khir. 2001;(8):49-51.
  • Aragona SE, Grassi FR, Nardi G, Lotti J, Mereghetti G, Canavesi E, Equizi E, Puccio AM , Lotti T. Photobiomodulation with polarized light in the treatment of cutaneous and mucosal ulcerative lesions. J Biol Regul Homeost Agents 2017;31:213-8.
  • Białożyt J., Materniak K., Kawecki M. 2018 Use of polarise lighting in support of treatment of pressure ulcers among patients after burns. Preliminary report. Dermatologia Estetyczna. vol.20, 1 (114)
  • Bolton P., Dyson M., Young S. The effect of polarized light on the release of growth factors from the U-937 macrophage-like cell line. J-STAGE/ Laser therapy, 1992 - / Volume 4 (1992) Issue 1
  • De Melo CA, Alves AN, Terena SM, Fernandes KP, Nunes FD, da Silva Dde F, Bussadori SK, Deana AM, Mesquita-Ferrari RA. Light-emitting diode therapy increases collagen deposition during the repair process of skeletal muscle. Lasers Med Sci. 2016 Apr;31(3):531-8.
  • Falus A, M. Fenyo M, Eder K, Madarasi A. Genome-wide gene expression study indicates the anti-inflammatory effect of polarized light in recurrent childhood respiratory disease. Inflamm. Res. (2011) 60: 965.
  • Fenyö M., Mandl J., Falus A. Opposite effect of linearly polarized light on biosynthesis of interleukin-6 in a human b lymphoid cell line and peripheral human monocytes. Cell Biology International, 1992 Volume26, Issue 3, P.265-269
  • Gasparyan LV, Brill G, Makela AM - Activation of angiogenesis under influence of red low level laser radiation Proceedings Volume 5968, Laser Florence 2005: A Window on the Laser Medicine World; 596806
  • Karu TI, Pyatibrat LV, Afanasyev NI. A Novel Mitochondrial Signaling Pathway Activated by Visible-to-near Infrared Radiation Photochemistry and Photobiology, 2004, 80: 366-372
  • Karu, Kolyakov SF Exact action spectra for cellular responses relevant to phototherapy. Photomedicine and Laser Therapy, 2005, Volume 23, Number 4, Pp. 355-361
  • Kislyi ND (2009) BIOPTRON Light Therapy in Dermatocosmetology. Guideline of the Federal Educational Agency / Russian People’s Friendship University, Moscow 2009
  • Kolenko 2017 Light therapy in complex treatment of patiens with herpes zoster. National Medical University named after O.O. Bogomolets, Kiev, Ukraine
  • Kubasova T, Horváth M, Kocsis K, Fenyö M. Effect of visible light on some cellular and immune parameters. Immunology and Cell Biology (1995) 73, 239-244
  • Lavi R, Shainberg A, Friedmann H, Shneyvays V, Rickover O, Eichler M, Kaplan D, Lubart R. Low energy visible light induces reactive oxygen species generation and stimulates an increase of intracellular calcium concentration in cardiac cells. J Biol Chem. 2003 Oct17;278(42):40917-22.
  • Mahmoud H. Mohamed, Mohamed N. Selem, Manar S. Mohamed, Heba Ali Abd EL-Ghaffaar. Interleukin-6 response to shock wave therapy versus polarized light therapy in the treatment of chronic diabetic foot ulcers. Drug Invention Today. Vol 11, Issue 11, 2019
  • Opel D. R., Hagstrom E., Pace A. K., Sisto K., Hirano-Ali S. A., Desai S., & Swan J. (2015). Light-emitting Diodes: A Brief Review and Clinical Experience. The Journal of Clinical and Aesthetic Dermatology, 8, 36–44.
  • Papageorgiou P,.Katsambas A, Chu,A Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris Britisli Journal of Dermatology 2000: 142: 973-978
  • Roberts JE. Visible light induced changes in the immune response through an eye-brain mechanism (photoneuroimmunology). J Photochem Photobiol B. 1995 Jul;29(1):3-15.
  • Samoilova Ka., Zhevago NA, Menshutina MA, Grigorieva NB Role of Nitric Oxide in the Visible Light-Induced Rapid Increase of Human Skin Microcirculation at the Local and Systemic Level. Photomedicine and Laser Surgery, 2008, Vol. 26, No. 5
  • Schindl A, Merwald H,.Schindl L, Kaun ‘C And.Wojta J Direct stimulatory effect of low-intensity 670 nm laser irradiation on human endothelial cell proliferation Britisli Journal of Dermatology 2003; 148: 334-336.
  • Young S, Bolton P, Dyson M, Harvey W, Diamantopoulos C. Macrophage responsiveness to light therapy. Lasers Surg Med. 1989;9(5):497-505
  • Zhevago N.A., Samoilova K.A. (2006) Pro- and anti-inflammatory cytokine content in the human peripheral blood after its transcutaneous and direct (in vitro) irradiation with polychromatic visible and infrared light. Photomedicine and Laser Surgery. 2006. Vol. 24(2). P.129-139.
  • Zhevago N.A., Samoilova K.A., Calderhead R.G. (2006) Polychromatic light similar to the terrestrial solar spectrum without its UV component stimulates DNA synthesis in human peripheral blood lymphocytes in vivo and in vitro. Photochemistry Photobiology. 2006. – Vol. 82(5). – P.1301-1308.

Sports medicine

  • Stasinopoulos D, Stasinopoulos I (2006) Comparison of effects of Cyriax physiother-apy, a supervised exercise programme and polarised polychromatic non-coherent light (Bioptron light) for the treatment of lateral epicondylitis. Clinical Rehabilitation 2006; 20: pp 12-23
  • Stasinopoulos D, Stasinopoulos I, Pantelis M, Stasinopoulou K (2009) Comparing the effects of exercise program and low-level laser therapy with exercise program and polarised polychromatic noncoherent light (BIOPTRON light) on the treatment of lateral elbow tendinopathy. Photomed laser surg 2009 Jun; 27(3): pp 513-520
  • Samoilova K.A., Zubanova O.I., Snopov S.A., Mukhuradze N.A., Mikhelson V.M. (1998) Single skin exposure to visible polarized light induces rapid modification of entire circulating blood. 2. Appearance of soluble factors restoring proliferation and chromosome structure in X-damaged lymphocytes. – Proc. SPIE, 1998, 3569: 26-33.
  • Samoilova KA, Bogacheva ON, Obolenskaya KD, Blinova MI, Kalmykova NV, Kuz-minikh EV (2004) Enhancement of the blood growth promoting activity after exposure of volunteers to visible and infrared polarized light. Part I: stimulation of human keratinocyte proliferation in vitro. Photochem Photobiol Sci 2004 Jan; 3(1): pp 96-101
  • Tamarova ZA, Limansky YP1, Gulyar SA. (2009) Antinociceptive effects of color polarized light in animal with formalin test. Fiziol. J.-2009.-V55, N§°3 – P.81-93
  • Wells J, Konrad P, Kao C, Jansen ED, Mahadevan-Jansen A. Pulsed laser versus electrical energy for peripheral nerve stimulation. J. Neurosci. Methods. Jul 2007. 163(2): 326–337.
  • Zlatkovic-Svenda MI, Leitner C, Biljana Lazovic BL , Petrovic DM. (2018) Complex Regional Pain Syndrome (Sudeck Atrophy) Prevention Possibility and Accelerated Recovery in Patients with Distal Radius at the Typical Site Fracture Using Polarized, Polychromatic Light
  • Therapy. Photobiomodulation, Phototherapy, and Laser Surgery Volume 37, N4.

Pain

  • M.F.Ballyzek, V.Vesovic-Potic, X.He, A.Johnston: Efficacy of polarized, polychromatic, non-coherent light in the treatment of chronic musculoskeletal neck and shoulder pain. Unpublished material, BIOPTRON AG, Wollerau, Switzerland (2005).
  • Stasinopoulos D. The use of polarized polychromatic non-coherent light as therapy for acute tennis elbow/lateral epicondylalgia: a pilot study. Photomedicine and Laser Surgery 2005;23(1):66-69.
  • D.Stasinopoulos, I.Stasinopoulos and M.I.Johnson: Treatment of carpal tunnel syndrome with polarized polychromatic noncoherent light (Bioptron light): a preliminary, prospective, open clinical trial. Photomedicine and Laser Surgery, 2005;23(2):225-228.
  • I.Stasinopoulos: Report of the rheumatology and rehabilitation centre. Unpublished material, Greece (1990).
  • Lymans'kyi I, Tamarova ZA, Huliar SO. [Suppression of visceral pain by action of the low intensity polarized light on acupuncture antinociceptive points]. Fiziol.Zh. 2003;49(5):43-51.
  • Ballyzek M.F.,Vesovic-Potic V, He X, Johnston A. (2005) Efficacy of polarized, polychromatic, non-coherent light in the treatment of chronic musculoskeletal neck and shoulder pain. Unpublished material, BIOPTRON AG, Wollerau, Switzerland (2005).
  • Bjordal JM , Couppé C , Chow RT , Tunér J and Ljunggren EA. (2003) A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Australian Journal of Physiotherapy. Vol. 49, P107-116 .
  • Gulyar S.A., Z.A. Tamarova. (2017) Analgesic Effects of the Polarized Red+Infrared LED Light. Journal of US-China Medical Science 14 (2017) 47-57
  • Gulyar S.A., Z.A. Tamarova. (2019) Comparison of the Analgesic Effect of Low-Intensive Polarized Polychromatic Light and Analgesics. Journal of US-China Medical Science 16 (2019) 1-15
  • Obolenskaya K.D., Samoilova K.A (2002). Comparative study of effects of polarized and non-polarized light on human blood in vivo and in vitro. I. Phagocytosis of monocytes and granulocytes. Laser Technology. –2002 – Vol. 12(2-3). P.7-13.
  • Petruzzi M, GM, Cocco F, della Vella F, Grassi R, Grassi FR. (2019) Polarized Polychromatic Noncoherent Light (Bioptron Light) as Adjunctive Treatment in Chronic Oral Mucosal Pain: A Pilot Study. Photobiomodulation, Photomedicine, and Laser SurgeryVol. 37, No. 4
  • Bjordal JM , Couppé C , Chow RT , Tunér J and Ljunggren EA. (2003) A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Australian Journal of Physiotherapy. Vol. 49, P107-116
  • Fulga C. Antiinflammatory effect of laser therapy in rheumatoid arthritis. Rom J Intern Med. 1998. 36(3-4): 273-279.

Dermatology

  • Leguina-Ruzzi A, Raichura KR, Tonks SK, Kwabi S, Leitner C. Treatment of non-atopic dermatitis with polarized Uv-free polychromatic light: a case report. Clinics and Practice 2019, vol. 9:1161
  • Aronis, A.Braziotis, K.Kafouros, N.Pagratis, Th.Papakostas and P.Venetsanos: The action of visible polarized light on skin diseases. Poster presentation at the 18th International Congress of Dermatology, New York, USA (1992).
  • Bartos Z.; The use of the BIOPTRON Light Therapy System in the treatment of skin disorders; Kiskunfélegyháza City Hospital and Polyclinic Department of Dermatological and Venerreal Diseases; Experience report; Hungary (2004).
  • Charakida Aikaterini, Deaton Edward D. Charakida Marietta, Mouser Paul et al.; Phototherapy in the Treatment of Acne Vulgaris. What is the Role?; Am J Clin Dermatol; 5(4):211-216(2004).
  • Bolton P., Dyson M., Young S. The effect of polarized light on the release of growth factors from the U-937 macrophage-like cell line. J-STAGE/ Laser therapy, 1992 - / Volume 4 (1992) Issue 1
  • Zhevago N.A., Samoilova K.A. (2006) Pro- and anti-inflammatory cytokine content in the human peripheral blood after its transcutaneous and direct (in vitro) irradiation with polychromatic visible and infrared light. Photomedicine and Laser Surgery. – 2006. – Vol. 24(2). – P.129-139.
  • Zhevago N.A., Samoilova K.A., Calderhead R.G. (2006) Polychromatic light similar to the terrestrial solar spectrum without its UV component stimulates DNA synthesis in human peripheral blood lymphocytes in vivo and in vitro. Photochemistry Photobiology. – 2006. – Vol. 82(5). – P.1301-1308.
  • Fenyö M., Mandl J., Falus A. Opposite effect of linearly polarized light on biosynthesis of interleukin‐6 in a human b lymphoid cell line and peripheral human monocytes. Cell Biology International, 1992 Volume26, Issue 3, P.265-269
  • Gasparyan LV, Brill G, Makela AM - Activation of angiogenesis under influence of red low level laser radiation Proceedings Volume 5968, Laser Florence 2005: A Window on the Laser Medicine World; 596806
  • Samoilova Ka., Zhevago NA, Menshutina MA, Grigorieva NB Role of Nitric Oxide in the Visible Light-Induced Rapid Increase of Human Skin Microcirculation at the Local and Systemic Level. Photomedicine and Laser Surgery, 2008, Vol. 26, No. 5
  • Karu TI, Pyatibrat LV, Afanasyev NI. A Novel Mitochondrial Signaling Pathway Activated by Visible-to-near Infrared Radiation Photochemistry and Photobiology, 2004, 80: 366-372
  • Karu, Kolyakov SF Exact action spectra for cellular responses relevant to phototherapy. Photomedicine and Laser Therapy, 2005, Volume 23, Number 4, Pp. 355-361
  • Kubasova T, Horváth M, Kocsis K, Fenyö M. Effect of visible light on some cellular and immune parameters. Immunology and Cell Biology Volume73, Issue3, June 1995, Pages 239-244
  • Lavi R, Shainberg A, Friedmann H, Shneyvays V, Rickover O, Eichler M, Kaplan D, Lubart R. Low energy visible light induces reactive oxygen species generation and stimulates an increase of intracellular calcium concentration in cardiac cells. J Biol Chem. 2003 Oct 17;278(42):40917-22.
  • Mahmoud H. Mohamed, Mohamed N. Selim, Nesreen M. Abo Raia, Ahmed Mahmoud Kadry. Ultrasonographic Response to Polarized Light Therapy in the Treatment of Atopic Dermatitis. EJPT.2022; 9:21-28
  • Roberts JE. Visible light induced changes in the immune response through an eye-brain mechanism (photoneuroimmunology). J Photochem Photobiol B. 1995 Jul;29(1):3-
  • Schindl A, Merwald H,.Schindl L, Kaun 'C And.Wojta J Direct stimulatory effect of low-intensity 670 nm laser irradiation on human endothelial cell proliferation Britisli Journal of Dermatology 2003; 148: 334-336.
  • Young S, Bolton P, Dyson M, Harvey W, Diamantopoulos C. Macrophage responsiveness to light therapy. Lasers Surg Med. 1989;9(5):497-505
  • De Melo CA, Alves AN, Terena SM, Fernandes KP, Nunes FD, da Silva Dde F, Bussadori SK, Deana AM, Mesquita-Ferrari RA. Light-emitting diode therapy increases collagen deposition during the repair process of skeletal muscle. Lasers Med Sci. 2016 Apr;31(3):531-8.
  • Opel D. R., Hagstrom E., Pace A. K., Sisto K., Hirano‐Ali S. A., Desai S., & Swan J. (2015). Light‐emitting Diodes: A Brief Review and Clinical Experience. The Journal of Clinical and Aesthetic Dermatology, 8, 36–44.
  • Colic, M.M., Vidojkovic N , Jovanovic, M., Lazovic, G The Use of Polarized Light in Aesthetic Surgery. Aesth. Plast. Surg. 28:324-327, 2004
  • Papageorgiou P,.Katsambas A, Chu,A Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris Britisli Journal of Dermatology 2000: 142: 973-978
  • Kislyi ND (2009) BIOPTRON Light Therapy in Dermatocosmetology. Guideline of the Federal Educational Agency / Russian People’s Friendship University, Moscow 2009.
  • Kolenko 2017 Light therapy in complex treatment of patiens with herpes zoster. National Medical University named after O.O. Bogomolets, Kiev, Ukraine

Pediatric

  • Burkin IA, Okateyev VS, 2004. The use of BIOPTRON Light Therapy in the treatment of children with musculoskeletal injuries. Clinical Experience Report. Traumatology Department, Sperandsky; Municipal Children's Hospital, Moscow, Russia.
  • Cerná O. The BIOPTRON Light Therapy in the life support and intensive care unit, Abstract, Congress Proceedings, Prague, Czechoslovakia 2005.
  • Khan MA, 2001, Report on use of BIOPTRON polychromatic incoherent polarized light in paediatrics, Experience Report. Russian Scientific Centre of Reconstructive Medicine and Balneotherapy, Moscow, Russia.
  • Khan MA, Erdes SI. Clinical efficiency of BIOPTRON polychromatic polarized light in the treatment of atopic dermatitis and frequent respiratory diseases in children, Allergology and Immunology in Paediatrics, N3 (14), September 2008.

SAD

  • Sit DK, McGowan J, Wiltrout C, Diler RS, Dills J, Luther J, Yang A, Ciolino J, Seltman H, Wisniewski SR, Terman M, Wisner KL. Adjunctive bright light therapy for bipolar depression: a randomized double-blind placebo-controlled trial. Am J Psychiatry 2018, 175:131-139
  • Sit D, Haigh S. Use of “lights” for bipolar depression. Current Psychiatry Reports, 2019, 21:45
  • Avery DA, Kizer D, Bolte MA et al.: Bright light therapy of subsydromal seasonal affective disorders in the workplace: morning vs. afternoon exposure. Acta Psychiatrica Scandinavica 2001; 103:267 -274.
  • Eastrnan Cl, Young MA, Fogg LF, Lìu L, Meaden PM: Bright light treatment of winter depression: a placebo-controlled trial. Arch Gen Psychiatry 1998; 55: BB3 - 889.
  • Lam RW and Levitt A: Canadian Consensus Guidelines for the Treatment of SAD, A Summary of the Report of the Canadian Consensus Group on SAD, Can J Diagnosis 1998; Suppl. 1 - l5.
  • Lee TM, Chan CC: Dose-response relationship of phototherapy for seasonal affective disorder: a meta'analysis. Acta Psychiatr Scand 1999; 99; 315 – 323.