Discover the Benefits of BIOPTRON Hyperlight Therapy in wound care

Effective and economical treatment for accelerated wound healing.

BIOPTRON^® Hyperlight Therapy is an extraordinary technology that offers an effective, fast and economical treatment for healing of all wound types, on any part of the body. It is used not only for the traumatic and post-operational wounds but also for burns, and non-healing wounds caused by vascular diseases, pressure or other health problems.

BIOPTRON^® Hyperlight Therapy considerably enhances the natural regeneration processes of the tissues, for faster wound healing with minimal scarring. It reduces the risk of infections carried by the open wounds, decreases the need of other treatments such as wound dressings, shortens the duration of hospitalization.

BIOPTRON^® Hyperlight is clinically tested and certified for the medical treatment of:

Wounds following trauma or surgery
Burns
Skin grafts
Venous leg ulcers (stasis ulcers)
Decubitus (pressure ulcers)
Diabetic foot ulcers

Wound Healing PHYSIOLOGICAL Process

Stimulation of endogenous purification

by removal of infectious micro-organisms and cell debris.

Stimulation of macrophages (bacterial) phagocytosis activity + (bacterial) phagocytosis capacity by formation of scavenger cells

Stimulation of neutrophils (number of neutrophils + phagocytosis activity)

Higher quality of granulation

by revascularisation and collagen production.

Release mediators

Release cytokines

Release growth factors

Stimulation of fibroblasts (

collagen production)

Stimulation of endothelium cells (= stimulation of angiogenesis)

Stimulation of cellular growth of fibroblasts

Faster epithelization

by accelerated proliferation and migration of epithelium cells, which can originate from the wound periphery and possibly from the wound.

Stimulation of keratinocytes (

formation of epithelium)

Stimulation of cellular growth of epithelium cells

Wound closure

Source: Bolton P., Dyson M., Young S. The effect of polarized light on the release of growth factors from the U-937 macrophage-like cell line. Laser Therapy 1992; 33-37.

Scientific Reference List

How does BIOPTRON^® Hyperlight treat wound?

Connective tissue

Secretion of collagen matrix

Migration to wound

FIBROBLAST

EPIDERMIS

DERMIS

Increases the proliferation and migration of fibroblasts

In every wound, the regeneration of tissues is a pivotal process. BIOPTRON^® Hyperlight increases the mobility of newly-formed fibroblasts, a critical process to wound healing. BIOPTRON^® Hyperlight promotes the expression of the binding factors that support this migration, contributing actively to the faster and healthier regeneration of the damaged skin.

(Bolton et al., 1992)

Increases collagen production

BIOPTRON^® Hyperlight increases the production of endogenous collagen, giving to the connective tissues the structure and stability necessary for elasticity and skin strength. BIOPTRON^® Hyperlight therapy fosters the recovery of tissues to a healthy and functional state.

(De Melo et al., 2016)

Improves microcirculation

BIOPTRON^® Hyperlight increases the blood flow in irradiated capillaries, boosting the oxygen and nutrients supply, as well as the uptake of nocive substances produced by damaged cells. BIOPTRON^® Hyperlight therapy provides to the new-formed cells all they need to favour healthy tissue regeneration.

(Samoilova et al., 2008)

Diminishes inflammation

BIOPTRON^® Hyperlight decreases the production of pro-inflammatory cytokines, such as TNF-α, and increases anti-inflammatory cytokines, such as TGF –β and IL-10, in the irradiated region, reducing locally the inflammation of affected epithelium.

(Falus et al 2011, Zhevago 2006)

Relieves pain

Constant and intolerable pain is disabling and devastating in patients with chronic wounds. Pain impairs wound healing and slows down patient recovery. BIOPTRON^® Hyperlight Therapy reduces pain by stimulating the production of nitric oxide, which decreases the over-stimulation of somatic peripheral nerves and increases vasodilatation, diminishing in parallel the ischemic pain.

(Gaspariyan et al., 2005; Samoilova et al., 2008)

Promotes angiogenesis

Chronic wounds are very often characterized by poor and deficient blood supply, which could slow down and delay the recovery. BIOPTRON^® Hyperlight promotes angiogenesis by developing new capillaries. The increased number and length of capillaries contribute to healthy tissue regeneration and shorter recovery time.

(Gasparyan et al., 2005)

Decreases the risk of infections and reinforces the immune system

Infections are a major risk factor in chronic open wounds that negatively affect wound management. BIOPTRON^® Hyperlight contains blue light, which is very well known for its intrinsic antimicrobial effect, without the addition of exogenous photosensitizers. The regular use of BIOPTRON^® Hyperlight prevents the development of bacterial infection.

(Opel et al, 2015)

In parallel, BIOPTRON^® Hyperlight Therapy increases IL-6, which increases the production of IgM antibodies by B lymphocytes, providing defence against blood-borne pathogens.

(Fenyo et al., 1992)

The secretion of IFN-γ is as well promoted, reinforcing the microbicidal and antiviral action of natural killer cells.

(Zhevago, 2006)

"SCAB"

EPIDERMIS

DERMIS

Cytokines

Fibroblast

Macrophages secreting cytokines

Blood vessels:

•cross-section

•longitudinal

Area of tissue repair

1

2

3

4

5

Legend:

Migration of macrophages to damaged area.
Secretion of cytokines and growth factors.
Fibroblast proliferation.
Collagen synthesis from fibroblasts.
Reinforced immune system and anti-microbicidal action.
Increased microcirculation and angiogenesis (growth of new blood vessels).

BIOPTRON^®Hyperlight heals wounds better, reduces pain, discomfort and scars

"The wound healing effects of BIOPTRON light therapy is undoubtedly associated with improvement of blood microcirculation, enhancement of the trophic function of blood, but also with increase of concentration in blood serum of growth factors and some cytokines"

Professor Samoilova, PhD, DSci,
Prof International leader in Photobiology and Photomedicine.

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